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CellOrganizer
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    • Helper Utilities
    • CellOrganizer for Matlab
      • Version 2.10
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CellOrganizer v2.9.3

 

Release Highlights

  • Significant additions have been made to the function (slml2report.m) for comparing two CellOrganizer spharm-obj models of organelle shape and spatial distribution. The report now includes 
    • improved plots of the spatial distributions of objects, and
    • a statistical comparison between the positions of objects (relative to cell and nuclear boundaries) in the two models.  This is done by forming a graph of the positions of all objects in both models, finding cliques within that graph, and measuring the fraction of objects from each model in each clique.  This is used to calculate the KL divergences between two random halves of the objects in each model (to establish a baseline measure for the single models), and between the four cross-model combinations of halves.  The higher the divergences of the cross-model pairs are compared to the within-model pairs, the more different the spatial distributions of the models are considered to be.
  • The execution time of the SPHARM-RPDM code for constructing cell, nucleus and organelle shape models has been improved through more efficient code for parts of the shape parameterization step contributed by Khaled Khairy (khaled.khairy@stjude.org).  Khaled is the Director of the Center for Bioimage Informatics at St. Jude Children’s Research Hospital in Memphis.  We gratefully acknowledge his contribution. (EqualAreaParametricMeshNewtonMethod.m, calc_area_jacobian_sphere_KK.m)
  • Improve object detection for spharm_obj models. (find_objects_local.m, find_objects_local.m, spharm_obj_model.m, spharm_obj_percell_3D.m)

Github Repository

      • Github

Downloads

      • CellOrganizer v2.9.3 Compressed Source Code [90.2 MB]

Documentation

      • To read the documentation online, click here.

Requirements

      • Matlab 2019b or newer
      • Bioinformatics Toolbox
      • Computer Vision System Toolbox
      • Control System Toolbox
      • Curve Fitting Toolbox
      • Image Processing Toolbox
      • Mapping Toolbox
      • Optimization Toolbox
      • Robust Control Toolbox
      • Signal Processing Toolbox
      • Simulink
      • Simulink Design Optimization
      • Statistics and Machine Learning Toolbox
      • System Identification Toolbox
      • Wavelet Toolbox

 

Validating Suite

CellOrganizer releases for the 2.0 family are continuously tested using a set of

      • public tests using the Matlab Unit Testing Framework
      • private tests for compatibility with old releases of Matlab

 

Compatibility

CellOrganizer releases for the 2.8+ family have been tested on

    • Matlab 2019b/Ubuntu 12.04
    • Matlab 2019b/MacOSX El Capitan

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Recent Posts

  • CellOrganizer v2.10 Released June 22, 2023
  • New Release! CellOrganizer v2.9.3 November 17, 2021
  • MMBioS 2021 Workshop July 29, 2021
  • New Release! CellOrganizer v2.9.2 July 13, 2021
  • New Release! CellOrganizer v2.9.1 July 12, 2021

Contact Us

If you have a question regarding any of the CellOrganizer products, then feel free to send us a message.

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Support for CellOrganizer has been provided by grants GM075205, GM090033 and GM103712 from the National Institute of General Medical Sciences, grants MCB1121919 and MCB1121793 from the U.S. National Science Foundation, by a Forschungspreis from the Alexander von Humboldt Foundation, and by the Freiburg Institute for Advanced Studies.

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